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lopinavir-loaded polymer nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)

F68
Type Polymer
Formula
Role core
2

octanoic acid sodium salt

sodium caprylate
Type Single Compound
Formula C8H15NaO2
Role layer
3

[1S-[1R*,(R*),3R*,4R*]]-N-[4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenyl-methyl)pentyl]tetrahydro-a-(1-methyl-ethyl)-2-oxo-1-(2H)-pyrimidineacetamide

lopinavir LPV
Type Single Compound
Formula C37H48N4O5
Role loaded material

Properties

General physical and chemical properties

Property Value Source
Zeta potential

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Applications

Area Application Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Source
Caco-2 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • [1S-[1R*,(R*),3R*,4R*]]-N-[4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenyl-methyl)pentyl]tetrahydro-a-(1-methyl-ethyl)-2-oxo-1-(2H)-pyrimidineacetamide
  • octanoic acid sodium salt
  • poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)
  1. UQBqkHXkQx
  2. vxHSv
Product

lopinavir-loaded polymer nanoparticles

Method 2

Type: Physical formation
Source:
Starting materials
  • [1S-[1R*,(R*),3R*,4R*]]-N-[4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenyl-methyl)pentyl]tetrahydro-a-(1-methyl-ethyl)-2-oxo-1-(2H)-pyrimidineacetamide
  • octanoic acid sodium salt
  • poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)
  1. ooNxUdqPUQ
  2. ow85Q
Product

lopinavir-loaded polymer nanoparticles

References

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