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α-methoxy-Ω-maleinimido tetra(ethylene glycol)-coated epidermal growth factor-grafted maleimide-PEG-linked 3-mercaptopropyltrimethoxy silane-functionalized silica-coated thioflavin T-loaded silicon nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

3-mercaptopropyltrimethoxy silane-functionalized silica-coated thioflavin T-loaded silicon nanoparticles

thiol-functionalized ThT-labeled SiO2/Si core-shell NP MPTMS-functionalized ThT-labeled SiO2-coated Si NP thiol-modified SiO2-coated ThT-incorporated SiNP
Type Nano Material
Formula
Role raw materials
2

maleimide-PEG

Type Polymer
Formula
Role graft
3

epidermal growth factor

EGF
Type Biomolecule
Formula
Role graft
4

alpha-methoxy-omega-maleinimido tetra(ethylene glycol)

α-methoxy-Ω-maleinimido tetra(ethylene glycol) maleimide-PEG
Type Polymer
Formula
Role graft

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Characterization

Method Nanomaterial Variant Source
differential centrifugal sedimentation

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Biological effects

Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • epidermal growth factor
  1. HOLbhHDLgIRH
Product

α-methoxy-Ω-maleinimido tetra(ethylene glycol)-coated epidermal growth factor-grafted maleimide-PEG-linked 3-mercaptopropyltrimethoxy silane-functionalized silica-coated thioflavin T-loaded silicon nanoparticles

Hydrodynamic diameter: 627 - 1966 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • epidermal growth factor
  1. cqjP6tVKfuu0
Product

α-methoxy-Ω-maleinimido tetra(ethylene glycol)-coated epidermal growth factor-grafted maleimide-PEG-linked 3-mercaptopropyltrimethoxy silane-functionalized silica-coated thioflavin T-loaded silicon nanoparticles

Size: not specified

Medium: minimum essential medium

Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • epidermal growth factor
  1. mqM6J0bRI2T1
Product

α-methoxy-Ω-maleinimido tetra(ethylene glycol)-coated epidermal growth factor-grafted maleimide-PEG-linked 3-mercaptopropyltrimethoxy silane-functionalized silica-coated thioflavin T-loaded silicon nanoparticles

Size: not specified

Medium: fetal bovine serum/minimum essential medium

Support: none

References

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