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methotrexate-loaded polycaprolactone/Phospholipon S100/octadecylamine nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

polycaprolactone

PCL
Type Polymer
Formula
Role core
2

[(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate

1-stearoyl-2- palmitoyl-sn-glycero-3-phosphocholine 1-palmitoyl-2-oleoyl-sn-glycero-3-phos-phocholine 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine 2-oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine palmitoyl-oleoyl-sn-glycero-phosphatidylcholine 1-palmitoyl-2-oleoylphosphatidylcholine palmitoyl oleoyl phosphatidylcholine palmitoyl-oleoyl-phosphatidylcholine palmitoyloleoyl-phosphatidylcholine palmitoyloleoylphosphatidyl choline Zwitterionic phosphatidylcholine L-α-phosphatidylcholine soy phosphatidylcholine phosphatidylcholine phospholipon 90 NG Phospholipon S100 PL S100 Egg-PC POPC POPS SPC PC EL
Type Single Compound
Formula C42H82NO8P
Role layer
3

1-octadecylamine

octadecylamine stearylamine ODA
Type Single Compound
Formula C18H39N
Role layer
4

methotrexate

abitrexate folex MTX
Type Single Compound
Formula C20H22N8O5
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
female Wistar rat with 7,12-dimethylbenz[a] anthracene (DMBA)-induced breast cancer

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • polycaprolactone
  • methotrexate
  1. TmqpFbDtb0RB
  2. Wt09guN
Product

methotrexate-loaded polycaprolactone/Phospholipon S100/octadecylamine nanoparticles

Hydrodynamic diameter: 112.36 - 121.76 nm

Medium/Support: none

References

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