Loading ...

Fast insight into nanotechnology

Access easily searchable nanoscience data, synthesis methods and literature

RAP-loaded ROS-responsive core-shell nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

oxidation-labile group-functionalized β-cyclodextrin

Ox-bCD
Type Biomolecule
Formula
Role core
2

lecithin

Type Complex Compound
Formula
Role layer
3

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]

DSPE-PEG
Type Polymer
Formula
Role loaded material
4

rapamycin

sirolimus RAPA RAP SR
Type Single Compound
Formula C51H79NO13
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on hydrogen peroxide presence

More information/entries available to subscribers only.

Or, view sample content

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

More information available to subscribers only.

Or, view sample content

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

More information available to subscribers only.

Or, view sample content

Biological effects

Biological system Test details Nanomaterial Variant Source
Sprague-Dawley rat vascular smooth muscle cells (VSMC)

More information/entries available to subscribers only.

Or, view sample content

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  • lecithin
  1. Lok1eF2pFlJDG5cGuUXnfR0va
  2. XbRGsoS
Product

RAP-loaded ROS-responsive core-shell nanoparticles

Hydrodynamic diameter: 195 - 205 nm

Medium: water

Support: none

References

Full content is available to subscribers only

To view content please choose from the following:

We use cookies to improve your experience with our site. More information

Sign up for a free trial