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DTX-loaded mPEG-PCL/PCL-g-PEI-g-PEG micelles

Based on

1 Articles
2016 Most recent source

Composition

1

methoxy poly(ethylene glycol)-poly(ε-caprolactone)

mPEG-PCL
Type Polymer
Formula
Role raw materials
2

PCL-g-PEI-g-PEG-Mal

Type Polymer
Formula
Role loaded material
3

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
Balb/c nude mouse with mouse mammary tumor 4T1 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  • methoxy poly(ethylene glycol)-poly(ε-caprolactone)
  • PCL-g-PEI-g-PEG-Mal
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  2. DX5xojC
  3. nqLBoKHkOmePqCo08mP
Product

DTX-loaded mPEG-PCL/PCL-g-PEI-g-PEG micelles

Size: not specified

Medium/Support: none

References

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