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pFLuc-loaded folate-conjugated cationic microbubble-derived nanovesicles

Based on

1 Articles
2016 Most recent source

Composition

1

octafluoropropane

perfluoropropane
Type Single Compound
Formula C3F8
Role core
2

1,2-dipalmitoyl-sn-glycero-phosphatidylcholine

dipalmitoyl phosphatidylcholine dipalmitoylphosphatidylcholine DPPC
Type Single Compound
Formula C40H80NO8P
Role layer
3

1,2-dipalmitoyl-3-trimethylammonium-propane

DPTAP
Type Single Compound
Formula C38H76ClNO4
Role loaded material
4

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000]

DSPE-PEG 2K
Type Polymer
Formula
Role loaded material
5

folate-conjugated 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000]

DSPE-PEG 2K-folate
Type Polymer
Formula
Role loaded material
6

FLuc plasmid DNA

pFLuc
Type Biomolecule
Formula
Role layer

Properties

Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
glioma C6 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000]
  • 1,2-dipalmitoyl-sn-glycero-phosphatidylcholine
  • 1,2-dipalmitoyl-3-trimethylammonium-propane
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Product

pFLuc-loaded folate-conjugated cationic microbubble-derived nanovesicles

Hydrodynamic diameter: 132.2 - 145.8 nm

Medium/Support: none

References

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