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docetaxel-loaded poly(cholesteryl butyrolactone-co-propylene oxide)/Pluronic F68 nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

poly(cholesteryl butyrolactone-co-propylene oxide)

poly(CBL-PO)
Type Polymer
Formula
Role core
2

Pluronic F68

Type Polymer
Formula
Role layer
3

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role loaded material

Properties

Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
male nude BALB/c mouse xenografted with squamous cell carcinoma SCC7 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  • poly(cholesteryl butyrolactone-co-propylene oxide)
  1. KzhhU0ZzGcVS6zDpAOtbVVU3
Product

docetaxel-loaded poly(cholesteryl butyrolactone-co-propylene oxide)/Pluronic F68 nanoparticles

Size: not specified

Medium/Support: none

References

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