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paclitaxel/sirolimus-conjugated levulinic acid-linked poly(ethylene glycol)-block-poly(β-benzyl L-aspartate) nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

Paclitaxel-conjugated levulinic acid-linked poly(ethylene glycol)-block-poly(β-benzyl L-aspartate)

PEG-LEV-PTX PEG-LEV-PX
Type Polymer
Formula
Role raw materials
2

rapamycin-conjugated levulinic acid-linked poly(ethylene glycol)-block-poly(β-benzyl L-aspartate)

PEG-LEV-RAP
Type Polymer
Formula
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on acidic pH conditions presence

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
female nu/nu athymic mouse

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Preparation

Method 1

Type: Physical formation
Source:
Product

paclitaxel/sirolimus-conjugated levulinic acid-linked poly(ethylene glycol)-block-poly(β-benzyl L-aspartate) nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • rapamycin-conjugated levulinic acid-linked poly(ethylene glycol)-block-poly(β-benzyl L-aspartate)
  • Paclitaxel-conjugated levulinic acid-linked poly(ethylene glycol)-block-poly(β-benzyl L-aspartate)
  1. M4kXCKcAU2Dk39H854
Product

paclitaxel/sirolimus-conjugated levulinic acid-linked poly(ethylene glycol)-block-poly(β-benzyl L-aspartate) nanoparticles

Hydrodynamic diameter: 95.3 - 109.3 nm

Medium: phosphate buffer solution

Support: none

References

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