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keyhole limpet hemocyanin-containing poly(lactide-co-glycolide) acid nanoparticles covered by monophosphoryl lipid A/1,2-dioleoyl-3-trimethylammonium-propane/1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)] carboxylic acid/cholesterol/rac-trans 3'-aminomethyl nicotine

Based on

1 Articles
2016 Most recent source

Composition

1

keyhole limpet hemocyanin-containing poly(lactide-co-glycolide) acid nanoparticles

KLH-containing PLGA nanoparticles
Type Nano Material
Formula
Role core
2

monophosphoryl lipid A/1,2-dioleoyl-3-trimethylammonium-propane/ 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)] carboxylic acid/cholesterol

MPLA/DOTAP/DSPE-PEG(2000) carboxylic acid/cholesterol
Type Complex Compound
Formula
Role layer
3

rac-trans 3'-aminomethyl nicotine

Type Single Compound
Formula C11H17N3
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
female BALB/c mouse

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Preparation

Method 1

Type: Physical formation
Source:
Product

keyhole limpet hemocyanin-containing poly(lactide-co-glycolide) acid nanoparticles covered by monophosphoryl lipid A/1,2-dioleoyl-3-trimethylammonium-propane/1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)] carboxylic acid/cholesterol/rac-trans 3'-aminomethyl nicotine

Size: 215.1 - 261.1 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • cholesterol
  • N,N,N-trimethyl-2,3-bis[(9Z)-9-octadecenoyloxy]-1-propanaminium
  • 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000] (ammonium salt)
See all (4)
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Product

keyhole limpet hemocyanin-containing poly(lactide-co-glycolide) acid nanoparticles covered by monophosphoryl lipid A/1,2-dioleoyl-3-trimethylammonium-propane/1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)] carboxylic acid/cholesterol/rac-trans 3'-aminomethyl nicotine

Size: not specified

Medium/Support: none

References

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