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DTX-loaded VES-g-ε-PLL nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role core
2

D-α-tocopherol grafted ε-polylysine conjugate

VES-g-ε-PLL
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
glioma C6 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  • D-α-tocopherol grafted ε-polylysine conjugate
  1. no3wFiFa0QJiWrkuHtUuGD
Product

DTX-loaded VES-g-ε-PLL nanoparticles

Hydrodynamic diameter: 29.03 - 34.97 nm

Size: ~ 30 nm

Medium/Support: none

References

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