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docetaxel-loaded methoxy poly(ethylene glycol)-poly(lactide)-poly(β-amino ester) micelles

Based on

1 Articles
2016 Most recent source

Composition

1

methoxy poly(ethylene glycol)-poly(lactide)-poly(β-amino ester)

MPEG-PLA-PAE
Type Polymer
Formula
Role carriers
2

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug release dependent on pH

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
human oropharyngeal epidermoid carcinoma KB cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  • methoxy poly(ethylene glycol)-poly(lactide)-poly(β-amino ester)
  1. tmO3u6NLXoCoL4GX4ridJ78L
Product

docetaxel-loaded methoxy poly(ethylene glycol)-poly(lactide)-poly(β-amino ester) micelles

References

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