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oligonucleotide-loaded hepatitis C virus non-structural protein 5A nanocapsules

Based on

1 Articles
2016 Most recent source

Composition

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

hepatitis C virus non-structural protein 5A crosslinked by 2,4-toluene diisocyanate

TDI-crosslinked NS5A
Type Biomolecule
Formula
Role layer
3

oligonucleotide

Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
female B6N-Tyr<sup>c-Brd</sup>/BrdCrCrl mouse

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • hepatitis C virus non-structural protein 5A
  • oligonucleotide
  • phosphate buffer solution
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  3. hIzS3dpm
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Product

oligonucleotide-loaded hepatitis C virus non-structural protein 5A nanocapsules

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Product

oligonucleotide-loaded hepatitis C virus non-structural protein 5A nanocapsules

Size: 428 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Product

oligonucleotide-loaded hepatitis C virus non-structural protein 5A nanocapsules

Size: 409 nm

Medium: cyclohexane

Support: none

References

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