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anti-EpCAM-modified leukocyte membrane fractions-coated magnetic nanoclusters

Based on

1 Articles
2016 Most recent source

Composition

1

azide-modified leukocyte membrane fractions-coated magnetic nanoclusters

N3-LMNC
Type Nano Material
Formula
Role core
2

dibenzocyclooctyne-PEG4 moiety

DBCO-PEG4 moiety
Type Single Compound
Formula -C32H39N2O9
Role layer
3

anti-EpCAM antibody

Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
confocal laser scanning microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
human breast cancer MCF-7 cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

anti-EpCAM-modified leukocyte membrane fractions-coated magnetic nanoclusters

Hydrodynamic diameter: ~ 150 - ~ 600 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Physical formation
Source:
Product

anti-EpCAM-modified leukocyte membrane fractions-coated magnetic nanoclusters

Hydrodynamic diameter: ~ 150 - ~ 500 nm

Medium: mouse whole blood

Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • dibenzocyclooctyne-PEG4-NHS ester
  • anti-EpCAM antibody
  1. QUc9Hgkn7lvCYGkQ
  2. v85x6PL
Product

anti-EpCAM-modified leukocyte membrane fractions-coated magnetic nanoclusters

Size: not specified

Medium/Support: none

References

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