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mRNA-loaded lipid nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

buffer solution

Type Complex Compound
Formula
Role core
2

C12-200/DOPE/cholesterol/C14-PEG mixture

Type Complex Compound
Formula
Role layer
3

scrambled erythropoietin mRNA

scrambled EPO mRNA
Type Biomolecule
Formula
Role loaded material

Properties

Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
female C57BL/6 mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,2-dimyristoyl-sn-glycero-3- phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium salt
  • (9Z)-9-octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester
  • cholesterol
See all (5)
  1. dSZ9P5wO5ZYBs1fMr8nBv8Pr2wEAsIMM6d
  2. pVpU
  3. 1OFTuVp1gKHd72W0ITQGEWTk
Product

mRNA-loaded lipid nanoparticles

Hydrodynamic diameter: 71 - 95 nm

Medium: buffer solution

Support: none

References

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