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nanovesicles containing PLI/FL-miR complexes

Based on

1 Articles
2016 Most recent source

Composition

1

poly(L-lysine-graft-imidazole)

poly(L-lysine-g-imidazole) PLI
Type Biomolecule
Formula
Role core
2

fluorescein-conjugated microRNA

fluorescein-conjugated miR fluorescein-labeled miRNA FL-miR
Type Biomolecule
Formula
Role loaded material
3

[(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate

1-stearoyl-2- palmitoyl-sn-glycero-3-phosphocholine 1-palmitoyl-2-oleoyl-sn-glycero-3-phos-phocholine 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine 2-oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine palmitoyl-oleoyl-sn-glycero-phosphatidylcholine 1-palmitoyl-2-oleoylphosphatidylcholine palmitoyl oleoyl phosphatidylcholine palmitoyl-oleoyl-phosphatidylcholine palmitoyloleoyl-phosphatidylcholine palmitoyloleoylphosphatidyl choline Zwitterionic phosphatidylcholine L-α-phosphatidylcholine soy phosphatidylcholine phosphatidylcholine phospholipon 90 NG Phospholipon S100 PL S100 Egg-PC POPC POPS SPC PC EL
Type Single Compound
Formula C42H82NO8P
Role layer
4

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material
5

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]

DSPE-mPEG
Type Polymer
Formula
Role loaded material

Properties

Applications

Characterization

Biological effects

Biological system Test details Source
BALB/c-nude mouse with gastric cancer MKN-74 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  • cholesterol
  • [(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
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  2. TZVL6ozp3aesDfw
  3. yOzmj015HYHmGcHs4MR78BEE6vM
Product

nanovesicles containing PLI/FL-miR complexes

References

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