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XL-184-loaded L-α-phosphatidylcholine/cholesterol/DSPE-PEG liposomes

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

water

Type Single Compound
Formula H2O
Role core
2

PC/cholesterol/DSPE-PEG mixture

Type Complex Compound
Formula
Role layer
3

cabozantinib

XL184
Type Single Compound
Formula C28H24FN3O5
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug release dependent on media

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Applications

Area Application Source
drug delivery

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
male Balb/c- nu/nu mouse bearing renal cell carcinoma ACHN xenograft

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renal cell carcinoma A498 cells
renal cell carcinoma ACHN cells

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • L-α-phosphatidylcholine
  • cabozantinib
See all (4)
  1. Wg7atCspp1ZTQ6crZk0kZ8COYjcW4F
Product

XL-184-loaded L-α-phosphatidylcholine/cholesterol/DSPE-PEG liposomes

References

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