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Cy7.5-loaded PLGA-based core-shell nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role core
2

lecithin

Type Complex Compound
Formula
Role layer
3

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]

DSPE-PEG
Type Polymer
Formula
Role loaded material
4

cyanine 7.5 N-hydroxysuccinimide ester

Cy7.5-N-hydroxysuccinimide ester Cy7.5 NHS ester Cy7.5-NHS Cy7.5
Type Single Compound
Formula C49H52ClN3O4
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
Sprague-Dawley rat with balloon catheter-induced injury in carotid artery (restenosis model)

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  • lecithin
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  2. 4o7tvHj
Product

Cy7.5-loaded PLGA-based core-shell nanoparticles

Hydrodynamic diameter: 199 - 207 nm

Medium: water

Support: none

References

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