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siRNA-loaded amine-functionalized MNC nanoparticles coated with mesoporous silica layer

Based on

4 Articles
2017 Most recent source

Composition

1

S,S-2-[3-[5-amino-1- carboxypentyl]ureido]pentanedioic acid-polyethylene glycol-block-poly(2-(diisopropyl amino)ethyl methacrylate):methoxy-polyethylene glycol-block-poly(2-(diisopropyl amino)ethyl methacrylate-co-glycidyl methacrylate-oligoarginine) nanoparticles

ACUPA-PEG-b-PDPA:Meo-PEG-b-P(DPA-co-GMA-R8) nanoparticles
Type Nano Material
Formula
Role carriers
2

small interfering RNA

Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
agarose gel electrophoresis map dependent on nitrogen-phosphorus ratio

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
B16F10-CD44<sup>+</sup> melanoma xenografted female C57BL/6 mice

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  1. PXhGiNFKeTT9mUUD
  2. lzmhxroQAcsVpVsp
Product

siRNA-loaded amine-functionalized MNC nanoparticles coated with mesoporous silica layer

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • S,S-2-[3-[5-amino-1- carboxypentyl]ureido]pentanedioic acid-polyethylene glycol-block-poly(2-(diisopropyl amino)ethyl methacrylate)
  • methoxy-polyethylene glycol-block-poly(2-(diisopropyl amino)ethyl methacrylate-co-glycidyl methacrylate-oligoarginine)
  • small interfering RNA
  1. kSS
Product

siRNA-loaded amine-functionalized MNC nanoparticles coated with mesoporous silica layer

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  1. CJkihJJ1iNBcwO3
Product

siRNA-loaded amine-functionalized MNC nanoparticles coated with mesoporous silica layer

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
  1. laVEjxBNc
Product

siRNA-loaded amine-functionalized MNC nanoparticles coated with mesoporous silica layer

Size: not specified

Medium/Support: none

References

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