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Trastuzumab-targeted Dox-loaded magnetic nanocarriers

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

superparamagnetic iron oxide nanoparticles

iron oxide nanoparticles SPION
Type Nano Material
Formula
Role core
2

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material
3

thiolated poly(MAA)-PVA graft copolymer

thiolated PVA-PMAA PMASH-modified PVA PMASH-grafted PVA PVA/PMASH PVA-PMASH
Type Polymer
Formula
Role layer
4

Trastuzumab

Tra
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Source
Zeta potential

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
human breast cancer MDA-MB-231 cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • Trastuzumab
  1. jffHJoVyYNaERD35cHpHosTOT
  2. XmVZ5D3We38RAlHvB0jxYgYqt2NW6XEIWMfasSFRm08BUNSywgNQ77pdjC3r6CjdeKb0urJOMwUr4xSiL1vUnXC
  3. HHZwRdh
  4. y6GigZoBwhVDkhgeNJ4nEcGUvkwyPYLdBNZ
Product

Trastuzumab-targeted Dox-loaded magnetic nanocarriers

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • Trastuzumab
  1. CWSRNZeEfNtMMmPdm7drRqHdD
  2. k5jvqo00UwBYV2E6SgtKYtVw7B3wZ4g9ATNxP97K5VNCeIYfE3bCW6cDKGoGhidAtnal6F2iu0lVrM508XITeyE
  3. hpIFjOp
  4. 8SZfHyEGp0KvmYWAeQ0HncfDUITYPO0TpsE
Product

Trastuzumab-targeted Dox-loaded magnetic nanocarriers

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • Trastuzumab
  1. TAypK4AnslDj53vtSNEf3s972
  2. WaLqHSqMRLfyfmsHLi8rg2U7P6y1U3JmBoZUiTQQaci9iTw2TUrS7VstpDkcX2SYnBtqEKguhpifQhYbjDLOIxa
  3. S4gHUDn
  4. 6rMcIdajHRylPUNtR3GGQDgVc5fkt52C9XH
Product

Trastuzumab-targeted Dox-loaded magnetic nanocarriers

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • Trastuzumab
  1. QIICrQ7pouKrjHR5Vz3qxLHIY
  2. BITjzhbaLBBzM7kpfEFY31qG1cDF76axLw65XxDTB3HZ4bFCSHZS871oLEQNkUO8j73cDGNDPF4ViWXw9NR6zfh
  3. xbJIlgu
  4. dT6D1revUbX6o9hZwOSCkBfBaBwpmf7Rrzc
Product

Trastuzumab-targeted Dox-loaded magnetic nanocarriers

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • Trastuzumab
  1. AEyuM7h2rh30yEjK5mvozoru2
  2. cVms9wO3WLquuckLqAMhkkTJPyXCjwFfp1XNsJW5x8xB8WTjSfmBP2V6OOjNhxn0gF1GoKvmmdt6AMwyvqoXb2C
  3. yn9LmsD
  4. 5PtWb81caqjwBlK2gl0m9VfXKDiX4RgSHxE
Product

Trastuzumab-targeted Dox-loaded magnetic nanocarriers

References

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