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lysozyme-encapsulating polyampholyte-modified liposomes

Based on

1 Articles
2016 Most recent source

Composition

1

phosphate buffer saline without calcium and magnesium

phosphate buffer solution PBS(-)
Type Complex Compound
Formula
Role core
2

lysozyme

Type Biomolecule
Formula
Role loaded material
3

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine

Δ9-cis-1,2-dioleoyl-sn-glycero-3-phosphocholine 1,2-dioleoyl- sn-glycero-3-phosphatidylcholine 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine 1,2-dioctanoyl-sn-glycero-3-phosphocholine 1,2- dioleoyl-sn-glycero-3-phosphocholine 1,2-dioleoyl-sn-glycero-3- phosphocholine 1,2-dioleoyl-sn-glycero-3-phosphocholine Δ9-cis-sn-glycero-3-phosphocholine dioleoyl-phosphatidyl choline dioleoylglycerophosphocholine dioleoylphosphatidylcholine dioleoylphosphocholine 18:1 (Δ9-cis) PC 18:1(cis) PC DC18:1PC DOPC PC
Type Single Compound
Formula C44H84NO8P
Role layer
4

(9Z)-9-Octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester

(9Z)-9-octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine 1,2-dioleoyl-sn-glycero-3-phosphorylethanolamine 1,2-dioctanoyl-sn-glycero-3-phosphoethanolamine 1,2-dioleoyl-sn-glycero- 3-phosphoethanolamine 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine 1,2-dioleoylphosphatidylethanolamine dioleoyl phosphatidylethanolamine dioleoylphosphatidylethanolamine Lipoid PE 18:1/18:1 DOPE
Type Single Compound
Formula C41H78NO8P
Role loaded material
5

ε-poly-L-lysine-dodecylsuccinic anhydride-succinic anhydride

PLL-DDSA-SA polyampholyte cryoprotectant PLL-DDSA-SA
Type Polymer
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
stability in aqueous medium

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
mouse fibroblast L929 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
  • ε-poly-L-lysine-dodecylsuccinic anhydride-succinic anhydride
  • (9Z)-9-Octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester
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Product

lysozyme-encapsulating polyampholyte-modified liposomes

Hydrodynamic diameter: ~ 280 nm

Medium: phosphate buffer saline without calcium and magnesium

Support: none

References

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