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mRNA-loaded modified dendrimer nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

2-tridecyloxirane-modified poly(amido amine) dendrimer generation 1

2-tridecyloxirane-modified PAMAM G1
Type Polymer
Formula
Role core
2

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]

mPEG2000-DMG
Type Polymer
Formula
Role layer
3

cytoplasmically expressed ovalbumin fragment-encoding mRNA

cOVA-encoding mRNA
Type Biomolecule
Formula
Role loaded material

Properties

Applications

Area Application Source
genetic engineering

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Characterization

Biological effects

Biological system Test details Source
wild-type CD45.1 mouse bearing OT-1 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  • 2-tridecyloxirane-modified poly(amido amine) dendrimer generation 1
  1. TCGaYMeJJsXrdplb3z
Product

mRNA-loaded modified dendrimer nanoparticles

References

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