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chloroquine/docetaxel-loaded PEG5K-b-PLA8K nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

poly(ethylene glycol)-block-poly(D,L-lactide)

PEG5K-b-PLA8K
Type Polymer
Formula
Role raw materials
2

chloroquine

CQ
Type Single Compound
Formula C18H26ClN3
Role loaded material
3

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug release

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Applications

Area Application Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Source
human breast adenocarcinoma ALDH<sup>hi</sup> MDA-MB-231 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  • chloroquine
  • poly(ethylene glycol)-block-poly(D,L-lactide)
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Product

chloroquine/docetaxel-loaded PEG5K-b-PLA8K nanoparticles

References

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