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emtansine liposome

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

water

Type Single Compound
Formula H2O
Role core
2

DOPE/DSPE-PEG

Type Complex Compound
Formula
Role layer
3

mertansine

emtansine DM1
Type Single Compound
Formula C35H48ClN3O10S
Role loaded material

Properties

Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
transmission electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
4T1 tumor bearing female nude BALB/c mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • (2-aminoethoxy)({2,3-bis[(9Z)-octadec-9-enoyloxy]propoxy})phosphinic acid
  • 1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine
  • mertansine
  1. lDu7ufBBBOvqMeuIz6u
Product

emtansine liposome

Size: not specified

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • (2-aminoethoxy)({2,3-bis[(9Z)-octadec-9-enoyloxy]propoxy})phosphinic acid
  • 1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine
  • mertansine
  1. nablRmUQl1FqxcllOUc
Product

emtansine liposome

Diameter: ~ 114.3 nm

Medium/Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • (2-aminoethoxy)({2,3-bis[(9Z)-octadec-9-enoyloxy]propoxy})phosphinic acid
  • 1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine
  • mertansine
  1. DNxs8cPXs2wI7mNZ2wu
Product

emtansine liposome

Diameter: ~ 62.37 nm

Medium/Support: none

References

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