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5-fluorouracil-loaded methoxy-poly(ethylene glycol)-poly(lactic-co-glycolic acid) nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

water

Type Single Compound
Formula H2O
Role core
2

methoxy-poly(ethylene glycol)-poly(lactic-co-glycolic acid)

mPEG-PLGA
Type Polymer
Formula
Role layer
3

5-fluoro-2,4(1H,3H)pyrimidinedione

5-Fluorouracil 5-fluorouracil fluorouracil Adrucil® Efudex® adrucil efudex 5-FU 5-Fu 5FU
Type Single Compound
Formula C4H3FN2O2
Role loaded material

Properties

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
transmission electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
C57BL/6 mouse xenografted with murine pancreatic cancer Pan02 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 5-fluoro-2,4(1H,3H)pyrimidinedione
  • methoxy-poly(ethylene glycol)-poly(lactic-co-glycolic acid)
  • water
  1. xfEuWi5GEdxWFuuiwiP38uzxM0I
  2. GloMhF0zT3
Product

5-fluorouracil-loaded methoxy-poly(ethylene glycol)-poly(lactic-co-glycolic acid) nanoparticles

Size: not specified

Medium/Support: none

References

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