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5-FU loaded dark-gold nanobeacons

Based on

1 Articles
2015 Most recent source

Composition

1

gold nanoparticles

Au nanoparticles gold NP Au NP AuNP GNP
Type Nano Material
Formula
Role core
2

α-mercapto-ω-carboxy PEG

Type Polymer
Formula
Role layer
3

anti MRP1

Type Biomolecule
Formula
Role layer
4

BHQ2 dark quencher

Type Biomolecule
Formula
Role layer
5

5-fluoro-2,4(1H,3H)pyrimidinedione

5-Fluorouracil 5-fluorouracil fluorouracil Adrucil® Efudex® adrucil efudex 5-FU 5-Fu 5FU
Type Single Compound
Formula C4H3FN2O2
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug release dependent on MR1/non-complementary target

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
triple-negative breast cancer MDA-MB-231 cells

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Preparation

References

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