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platinum-conjugated PAMAM

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

fourth generation poly(amidoamine) dendrimer

PAMAM
Type Nano Material
Formula
Role raw materials
2

4-[(diaminodichlorohydroxyplatinio)oxy]-4-oxobutanoic acid moiety

cisplatin prodrug moiety
Type Single Compound
Formula -C4H11Cl2N2O4Pt
Role graft

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Characterization

Method Nanomaterial Variant Source
nuclear magnetic resonance spectroscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c nude mouse bearing BxPC-3 xenograft tumor

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • -C3H4O-
  • 4-[(diaminodichlorohydroxyplatinio)oxy]-4-oxobutanoic acid
Product

platinum-conjugated PAMAM

Diameter: 5.4 - 7.0 nm

Medium/Support: none

References

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