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RGD peptide-conjugated doxorubicin-loaded selenium nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

selenium

Type Single Compound
Formula Se
Role core
2

chitosan

Type Biomolecule
Formula
Role layer
3

N-(2-Carboxyethyl)maleimide

3-maleimide propionic acid 3-maleimidopropionic acid N-maleoyl-β-alanine
Type Single Compound
Formula C7H7NO4
Role graft
4

RGR peptide

Type Single Compound
Formula C15H27N7O6S
Role graft
5

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug release dependent on cell lysate presence

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
fluorescence spectroscopy

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Biological effects

Biological system Test details Source
C57BL/6 mouse xenografted with human breast cancer MCF-7 cells

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human umbilical vein endothelial cells

Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • adriblastin
  • sodium selenite
  1. QeQ8gz7ugXxNmPfn
  2. 3xM2LVBpX0IwX
Product

RGD peptide-conjugated doxorubicin-loaded selenium nanoparticles

References

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