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cyanine 5-attached/folic acid-functionalized single-stranded DNA-modified gold nanoparticles pyramids

Based on

1 Articles
2016 Most recent source

Composition

1

Cy5-modified reporter sequence/telomerase primer-attached single-stranded DNA-modified gold nanoparticles pyramids

Cy5-RS/TP-attached ssDNA-modified Au NP pyramids
Type Nano Material
Formula
Role core
2

thiol-poly(ethylene glycol) 2000-folic acid

SH-PEG2000-FA
Type Polymer
Formula
Role layer

Properties

Sensor properties

Type of sensor Sensor property Nanomaterial Variant Source
compounds sensor for telomerase in breast cancer MCF-7 cells

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Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
cryo-electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
K562 cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • thiol-poly(ethylene glycol) 2000-amine
  • folate acid
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Product

cyanine 5-attached/folic acid-functionalized single-stranded DNA-modified gold nanoparticles pyramids

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Product

cyanine 5-attached/folic acid-functionalized single-stranded DNA-modified gold nanoparticles pyramids

Hydrodynamic diameter: 65.7 - 70.3 nm

Medium: phosphate buffer solution

Support: none

References

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