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cisplatin prodrug-conjugated poly(ethylene glycol)-b-poly(cyclohexyl ethyl methacrylate)-modified PAMAM dendrimer

Based on

1 Articles
2016 Most recent source

Composition

1

fourth generation poly(amidoamine) dendrimer

PAMAM
Type Nano Material
Formula
Role raw materials
2

4-[(diaminodichlorohydroxyplatinio)oxy]-4-oxobutanoic acid moiety

cisplatin prodrug moiety
Type Single Compound
Formula -C4H11Cl2N2O4Pt
Role graft
3

N-(ε-maleimidocaproyloxy)-terminated poly(ethylene glycol)-b-poly(cyclohexyl ethyl methacrylate) moiety

PEG-b-PCHMA moiety
Type Polymer
Formula
Role graft

Properties

Applications

Characterization

Method Source
chromatography

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Biological effects

Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • N-(ε-maleimidocaproyloxy)succinimide ester-terminated poly(ethylene glycol)-b-poly(cyclohexyl ethyl methacrylate)
  • platinum-conjugated PAMAM
  1. fqJ6UokCeMWVpwNbQ
  2. t0JIR
  3. wOSm
Product

cisplatin prodrug-conjugated poly(ethylene glycol)-b-poly(cyclohexyl ethyl methacrylate)-modified PAMAM dendrimer

References

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