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Cy5.5-Gd(III) ions-functionalized dendrimer G5-entrapped Au NP nanocomposite probe

Based on

1 Articles
2016 Most recent source

Composition

1

gold nanoparticles

Au nanoparticles gold NP Au NP AuNP GNP
Type Nano Material
Formula
Role core
2

poly(amido amine) dendrimer generation 5

PAMAM dendrimer G5
Type Polymer
Formula
Role layer
3

1,4,7,10-tetraazacyclododecane-N,-N',N'',N'''-tetraacetic acid

1,4,7,10- tetraazacyclododecane-1,4,7,10-tetraacetic acid 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid tetraazacyclododecane-1,4,7,10-tetraacetic acid cyclododecane DOTA CCD
Type Single Compound
Formula C16H28N4O8
Role layer
4

FA-PEG-COOH

Type Polymer
Formula
Role layer
5

carboxyl group-terminated PEG monomethyl ether

mPEG-COOH
Type Polymer
Formula
Role layer
6

N-hydroxysuccinimide ester modified Cy5.5

cyanine 5.5 N-hydroxysuccinimide ester cyanine5.5 N-hydroxysuccinimide ester hydroxysuccinimide ester of Cy5.5 Cy5.5 N-hydroxysuccinimide ester Cy5.5-N-hydroxysuccinimide ester cyanine 5.5 NHS ester Cyanine5.5 NHS ester Cy5.5 NHS ester Cy5.5-NHS ester Cy5.5-NHS-ester cyanine dye Cy5.5-NHS NHS-Cy5.5 Cy5.5
Type Single Compound
Formula C44H46N3O4Cl
Role layer
7

gadolinium(III) cation

gadolinium(III) ion gadolinium cation cationic Gd ion gadolinium(III) gadolinium ion gadolinium(3+) Gd(III) ion Gd(3+) ion Gd3+ ion Gd ion Gd(3+) Gd3+
Type Single Compound
Formula Gd3+
Role layer

Properties

Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/C nude mouse-bearing NCI-H460 tumor

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Preparation

Method 1

Type: Physical formation
Source:
Product

Cy5.5-Gd(III) ions-functionalized dendrimer G5-entrapped Au NP nanocomposite probe

Hydrodynamic size: ~ 126.0 nm

Medium: water

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • 2,2',2''-(10-(2-((2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl) tetraacetic acid
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Product

Cy5.5-Gd(III) ions-functionalized dendrimer G5-entrapped Au NP nanocomposite probe

Size: not specified

Medium/Support: none

References

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