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gadolinium-loaded rhodamine-labeled PAMAM-G5/PEG/DOTA

Based on

1 Articles
2016 Most recent source

Composition

1

PAMAM dendrimer G5

Type Polymer
Formula
Role core
2

polyethylene glycol-carboxyl

PEG-COOH
Type Polymer
Formula
Role layer
3

1,4,7,10-tetraazacyclododecane-N,-N',N'',N'''-tetraacetic acid

1,4,7,10- tetraazacyclododecane-1,4,7,10-tetraacetic acid 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid tetraazacyclododecane-1,4,7,10-tetraacetic acid cyclododecane DOTA CCD
Type Single Compound
Formula C16H28N4O8
Role layer
4

gadolinium atom

gadolinium
Type Single Compound
Formula Gd
Role loaded material
5

rhodamine

Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
T1-weighed relaxivity (r1p )

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
C57BL/6J mouse

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • rhodamine succinimide ester
  • PAMAM dendrimer G5
  1. LMqG9dXRRErV1MbFoGKsQ
Product

gadolinium-loaded rhodamine-labeled PAMAM-G5/PEG/DOTA

Hydrodynamic diameter: 11.5 nm

Medium/Support: none

References

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