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anti-Factor VII siRNA-loaded dendrimer/PEG-lipid/DSPC/cholesterol nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

dendrimer/PEG-lipid/DSPC/cholesterol mixture

Type Complex Compound
Formula
Role carriers
2

siRNA against Factor VII

siRNA against FVII siFVII
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
genetic engineering

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
female C57BL/6 mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • [(2R)-2,3-di(octadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
  • cholesterol
  • C93H173N5O20S5
See all (4)
  1. CouP66LiN3aIHDkQIc
Product

anti-Factor VII siRNA-loaded dendrimer/PEG-lipid/DSPC/cholesterol nanoparticles

Hydrodynamic diameter: ~ 40 - ~ 120 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • [(2R)-2,3-di(octadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
  • C168H309N7O36S9
See all (4)
  1. 1pO8Pyw399MkkNyxuN
Product

anti-Factor VII siRNA-loaded dendrimer/PEG-lipid/DSPC/cholesterol nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • [(2R)-2,3-di(octadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
  • C136H254N4O24S6
See all (4)
  1. MbQUGO2Oq89Xbmsva8
Product

anti-Factor VII siRNA-loaded dendrimer/PEG-lipid/DSPC/cholesterol nanoparticles

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • [(2R)-2,3-di(octadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
  • C78H144N4O16S4
See all (4)
  1. LReeJ0mF6MEIzAdpyn
Product

anti-Factor VII siRNA-loaded dendrimer/PEG-lipid/DSPC/cholesterol nanoparticles

Size: not specified

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • C135H252N4O24S6
  • [(2R)-2,3-di(octadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
  • cholesterol
See all (4)
  1. bS3SWfgQfbbDBFZVDz
Product

anti-Factor VII siRNA-loaded dendrimer/PEG-lipid/DSPC/cholesterol nanoparticles

Size: not specified

Medium/Support: none

References

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