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Nile red-doped Paclitaxel@tannic acid-FeIII complex nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

Paclitaxel

Abraxane Plaxicel Paxene Taxol PAC PCL PTX PX
Type Single Compound
Formula C47H51NO14
Role core
2

tannic acid-FeIII complex

TA-FeIII complex
Type Complex Compound
Formula
Role layer
3

(17S,18S)-18-(2-carboxyethyl)-20-(carboxymethyl)-12-ethenyl-7-ethyl-3,8,13,17-tetramethyl-17,18,22,23-tetrahydroporphyrin-2-carboxylic acid

13-carboxy-17-(2-carboxyethyl)-15-carboxymethyl-17,18-trans-dihydro-3-vinyl-8-ethyl-2,7,12,18-tetramethylporphyrin Chlorin e6 chlorin e6 Chlorin Ce6
Type Single Compound
Formula C34H36N4O6
Role dopant

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c nude mouse bearing MCF-7 tumor

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • 8-(diethylamino)-12H-10-oxa-5-azatetraphen-12-one
  • Paclitaxel
  1. BXzeZmZIGkit1vgq
Product

Nile red-doped Paclitaxel@tannic acid-FeIII complex nanoparticles

Diameter: 120 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • (17S,18S)-18-(2-carboxyethyl)-20-(carboxymethyl)-12-ethenyl-7-ethyl-3,8,13,17-tetramethyl-17,18,22,23-tetrahydroporphyrin-2-carboxylic acid
  • Paclitaxel
  1. VtnHy8FakraZocP1
Product

Nile red-doped Paclitaxel@tannic acid-FeIII complex nanoparticles

Diameter: 120 nm

Medium/Support: none

Method 3

Type: Physical formation
Source:
Product

Nile red-doped Paclitaxel@tannic acid-FeIII complex nanoparticles

Diameter: 120 nm

Hydrodynamic diameter: ~ 100 nm

Medium: water

Support: none

References

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