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poly(lactic-co-glycolic acid)/poly(lactic-co-glycolic acid)-polyarginine/1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol) nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role core
2

1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol)

DSPE-PEG
Type Polymer
Formula
Role layer
3

poly(lactic-co-glycolic acid)-polyarginine

PLGA-PLR
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c mouse

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • 1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol)
  • poly(lactic-co-glycolic acid)
  • poly(lactic-co-glycolic acid)-polyarginine
  1. P89O5YE63biAU
Product

poly(lactic-co-glycolic acid)/poly(lactic-co-glycolic acid)-polyarginine/1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol) nanoparticles

Hydrodynamic diameter: 38.8 - 46.4 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • 1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol)
  • poly(lactic-co-glycolic acid)
  • poly(lactic-co-glycolic acid)-polyarginine
  1. NQw6NwVrWz2xr
Product

poly(lactic-co-glycolic acid)/poly(lactic-co-glycolic acid)-polyarginine/1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol) nanoparticles

Hydrodynamic diameter: 37.0 - 44.0 nm

Medium/Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • 1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol)
  • poly(lactic-co-glycolic acid)
  • poly(lactic-co-glycolic acid)-polyarginine
  1. 7FfQHsulryiMF
Product

poly(lactic-co-glycolic acid)/poly(lactic-co-glycolic acid)-polyarginine/1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol) nanoparticles

Hydrodynamic diameter: 40.2 - 49.6 nm

Medium/Support: none

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • 1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol)
  • poly(lactic-co-glycolic acid)
  • poly(lactic-co-glycolic acid)-polyarginine
  1. X2Z3yD4tH1rSl
Product

poly(lactic-co-glycolic acid)/poly(lactic-co-glycolic acid)-polyarginine/1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol) nanoparticles

Hydrodynamic diameter: 41.5 - 49.9 nm

Medium/Support: none

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • 1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol)
  • poly(lactic-co-glycolic acid)
  • poly(lactic-co-glycolic acid)-polyarginine
  1. i8IMiACMnCRlK
Product

poly(lactic-co-glycolic acid)/poly(lactic-co-glycolic acid)-polyarginine/1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol) nanoparticles

Hydrodynamic diameter: 34.2 - 46.8 nm

Medium/Support: none

References

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