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poly(lactic-co-glycolic acid)/poly(lactic-co-glycolic acid)-polyarginine/1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol) nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role core
2

1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol)

DSPE-PEG
Type Polymer
Formula
Role layer
3

poly(lactic-co-glycolic acid)-polyarginine

PLGA-PLR
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c mouse

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • 1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol)
  • poly(lactic-co-glycolic acid)
  • poly(lactic-co-glycolic acid)-polyarginine
  1. rmtdDhnAp6BxB
Product

poly(lactic-co-glycolic acid)/poly(lactic-co-glycolic acid)-polyarginine/1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol) nanoparticles

Hydrodynamic diameter: 42.7 - 48.5 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • 1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol)
  • poly(lactic-co-glycolic acid)
  • poly(lactic-co-glycolic acid)-polyarginine
  1. WPfGMS2CUO4sp
Product

poly(lactic-co-glycolic acid)/poly(lactic-co-glycolic acid)-polyarginine/1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol) nanoparticles

Hydrodynamic diameter: ~ 40 - 44 nm

Medium/Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • 1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol)
  • poly(lactic-co-glycolic acid)
  • poly(lactic-co-glycolic acid)-polyarginine
  1. 6y1wCUy5VZQBc
Product

poly(lactic-co-glycolic acid)/poly(lactic-co-glycolic acid)-polyarginine/1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol) nanoparticles

Hydrodynamic diameter: 36.9 - 43.5 nm

Medium/Support: none

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • 1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol)
  • poly(lactic-co-glycolic acid)
  • poly(lactic-co-glycolic acid)-polyarginine
  1. 1UQT8yzJHgohg
Product

poly(lactic-co-glycolic acid)/poly(lactic-co-glycolic acid)-polyarginine/1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol) nanoparticles

Hydrodynamic diameter: 36.8 - 43.8 nm

Medium/Support: none

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • 1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol)
  • poly(lactic-co-glycolic acid)
  • poly(lactic-co-glycolic acid)-polyarginine
  1. j7s5yQHkOWj8n
Product

poly(lactic-co-glycolic acid)/poly(lactic-co-glycolic acid)-polyarginine/1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol) nanoparticles

Hydrodynamic diameter: 40.2 - 49.4 nm

Medium/Support: none

References

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