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DiI/Cy5-labeled (1,2-di-(9Z-octadecenoyl)-3-biguanide-propane lipid-protamine-DNA/anisamide nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

water

Type Single Compound
Formula H2O
Role core
2

protamine

Type Biomolecule
Formula
Role carriers
3

Cy5-labeled deoxyribonucleic acid

Cy5-labeled DNA
Type Biomolecule
Formula
Role loaded material
4

1,2-di(9Z-octadecenoyloxy)-3-trimethylammonium-propane chloride

N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium chloride 1,2-di-(9Z-octadecenoyl)-3-trimethylammonium-propane chloride 1,2-dioleoyl-3-trimethyl-ammonium-propane (chloride salt) (1,2-dioleoyloxypropyl)-N,N,N-trimethylammonium chloride 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) 1,2-dioleoyl-3-trimethylammonium-propane chloride salt 1,2-dioleoyl-3-trimethylammoniumpropane chloride salt 1,2-dioleoyloxy-3-trimethylammonium-propane chloride 1,2-dioleoyl-3-trimethyl-ammonium-propane chloride (2,3-dioleoyloxypropyl)trimethylammonium chloride 1,2-dioleoyl-3-(trimethylammonio)propane chloride 1,2-dioleoyl-3-trimethylammonium-propane chloride 2,3-dioleoyloxy-propyl-trimethylammonium chloride 1,2-di-O-octadecenyl-3-trimethylammonium-propane 1,2-dioleoyl-3-trimethylammoniumpropane chloride dioleoyltrimethyl-ammoniumpropane chloride DOTAP (chloride salt) DOTAP chloride DOTAP DOTMA
Type Single Compound
Formula C42H80ClNO4
Role layer
5

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material
6

1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine

distearoyl phosphatidylethanolamine distearoylphosphatidylethanolamine distearoyl phoshatidylethanolamine distearoylphoshatidylethanolamine DSPE
Type Single Compound
Formula C41H82NO8P
Role loaded material
7

poly(ethylene glycol)

poly(ethylene oxide) polyethylene glycol polyethylene oxide polyoxyethylene PEG PEO POE
Type Polymer
Formula
Role layer
8

poly(ethylene glycol)/anisamide

PEG-anisamide
Type Polymer
Formula
Role layer
9

2-[(1E)-3-[(2Z)-3,3-dimethyl-1-octadecyl-2,3-dihydro-1H-indol-2-ylidene]prop-1-en-1-yl]-3,3-dimethyl-1-octadecyl-3H-indol-1-ium perchlorate

3H-indolium, 2-[3-(1,3-dihydro-3,3-dimethyl-1-octadecyl-2H-indol-2-ylidene)-1-propenyl]-3,3-dimethyl-1-octadecyl-, perchlorate 3H-indolium, 2-[3-(1,3-dihydro-3,3-dimethyl-1-octadecyl-2H-indol-2-ylidene)-1-propenyl]-3,3-dimethyl-1-octadecyl-perchlorate (2Z)-2-[(E)-3-(3,3-dimethyl-1-octadecylindol-1-ium-2-yl)prop-2-enylidene]-3,3-dimethyl-1-octadecylindole perchlorate 1,1';-dioctadecyl-3,3,3';,3';-tetramethylindocarbocyanine perchlorate 1,1'-dioctadecyl-3,3,3',3'-tetramethylindodicarbocyanine perchlorate 1,1'- dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate 1,1'-dioctadecyl-3,3,3',3'-tetra-methylindocarbocyanine perchlorate 1,1'-dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate 1,1'-dioctadecyl-3,3,3'3'-tetramethylindocarbocyanine perchlorate 1,1-dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate DiI-C18 lipophilic membrane dye carbocyanine-based fluorophore fluorescent whitening agent fluorescent dye D-282 DiIC18(3)) DiIC18(3) DiI-ClO4 DiI-C18 Dye Aye DiIC18 DiD DIL DiI Dil FWA
Type Single Compound
Formula C59H97ClN2O4
Role loaded material

Properties

Applications

Characterization

Biological effects

Biological system Test details Source
human non-small-cell lung cancer H460 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • 2-[(1E)-3-[(2Z)-3,3-dimethyl-1-octadecyl-2,3-dihydro-1H-indol-2-ylidene]prop-1-en-1-yl]-3,3-dimethyl-1-octadecyl-3H-indol-1-ium perchlorate
  • 1,2-di-(9Z-octadecenoyl)-3-biguanide-propane
  1. GG9oD7byw84EDUMZCe1
Product

DiI/Cy5-labeled (1,2-di-(9Z-octadecenoyl)-3-biguanide-propane lipid-protamine-DNA/anisamide nanoparticles

References

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