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PEG-PCX/siNCOA3 polyplexes

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

PEGylated polymeric CXCR4 inhibitor

PEGylated PCX PEG-PCX
Type Polymer
Formula
Role raw materials
2

stability enhanced NCOA3 siRNA

NCOA3-silencing siRNA siNCOA3
Type Biomolecule
Formula
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human epithelial osteosarcoma U2OS cells stably expressing EGFP-CXCR4 fusion protein

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • HEPES-buffered glucose
  • stability enhanced NCOA3 siRNA
  • PEGylated polymeric CXCR4 inhibitor
Product

PEG-PCX/siNCOA3 polyplexes

Hydrodynamic diameter: ~ 90 nm

Medium: HEPES-buffered glucose

Support: none

References

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