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siRNA-loaded hyaluronan-functionalized calcium phosphate nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

β-tricalcium phosphate

calcium orthophosphate tricalcium phosphate calcium phosphate β-TCP CaPh TCP CaP CP
Type Single Compound
Formula Ca3(PO4)2
Role core
2

AHA25

Type Complex Compound
Formula
Role layer
3

siRNA

Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
A549 cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

siRNA-loaded hyaluronan-functionalized calcium phosphate nanoparticles

Size: not specified

Medium: FBS/PBS

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • HEPES buffer
  • AHA25
  • calcium(II) chloride
See all (4)
  1. WSg8N
  2. ukVF
Product

siRNA-loaded hyaluronan-functionalized calcium phosphate nanoparticles

Hydrodynamic diameter: 215.8 - 256.4 nm

Medium: HEPES buffer

Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • AHA10
  • calcium(II) chloride
  • siRNA
  1. BAJSzs0woLcy
  2. Akgm6
  3. PPWA
Product

siRNA-loaded hyaluronan-functionalized calcium phosphate nanoparticles

Size: not specified

Medium/Support: none

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • HEPES buffer
  • AHA10
  • calcium(II) chloride
See all (4)
  1. iQUS4
  2. 3IJ8
Product

siRNA-loaded hyaluronan-functionalized calcium phosphate nanoparticles

Hydrodynamic diameter: 166.6 - 183.2 nm

Medium: HEPES buffer

Support: none

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • AHA25
  • calcium(II) chloride
  • siRNA
  1. 15QtYqYqBrtx
  2. G1wBl
  3. clP3
Product

siRNA-loaded hyaluronan-functionalized calcium phosphate nanoparticles

Size: not specified

Medium/Support: none

References

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