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DOX/DOX-S-DEVD-loaded heparin nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

heparin sodium

heparin
Type Biomolecule
Formula
Role core
2

Ac-KGDEVD-PABC-DOX

DEVD-S-DOX
Type Biomolecule
Formula
Role loaded material
3

doxorubicin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material
4

Pluronic F-68

Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
C<sub>3</sub>H/HeN mouse with murine squamous cell carcinoma SCC-7 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • Ac-KGDEVD-PABC-DOX
  • heparin sodium
  • doxorubicin
  1. DYgwMYmTcOaQJjLvh
Product

DOX/DOX-S-DEVD-loaded heparin nanoparticles

Diameter: ~ 100 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
Product

DOX/DOX-S-DEVD-loaded heparin nanoparticles

Hydrodynamic diameter: ~ 70 - 150 nm

Medium: phosphate buffer solution

Support: none

References

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