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mitoxantrone-encapsulated phosphate-based pillar[6]arene/alkyl-modified pyridinium bromide supramolecular nanocarriers

Based on

1 Articles
2016 Most recent source

Composition

1

water

Type Single Compound
Formula H2O
Role core
2

phosphate-based pillar[5]arene/alkyl-modified pyridinium bromide

Type Complex Compound
Formula
Role layer
3

1,4-dihydroxy-5,8-bis({2-[(2-hydroxyethyl)amino]ethyl}amino)anthracene-9,10-dione

1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino) ethylamino]-anthracene-9,10-dione mitoxantrone mitox MTO MTX Mit
Type Single Compound
Formula C22H28N4O6
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
A549 cancer cell line

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • water
  • C66H86Na12O48P12
  • C28H37BrN2
  1. 785NpfZ
Product

mitoxantrone-encapsulated phosphate-based pillar[6]arene/alkyl-modified pyridinium bromide supramolecular nanocarriers

Hydrodynamic diameter: ~ 293.1 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Product

mitoxantrone-encapsulated phosphate-based pillar[6]arene/alkyl-modified pyridinium bromide supramolecular nanocarriers

Thickness: ~ 4 nm

Medium/Support: none

References

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