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tenofovir-loaded Eudragit S-100® nanoparticles

Based on

1 Articles
1 Patents
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

polyurethane

Type Polymer
Formula
Role carriers
2

({[(2R)-l-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid

({[(2R)-l-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid (R)-9-(2-phosphonylmethoxypropyl)-adenine (R)-9-[2-(phosphonomethoxy)propyl]adenine tenofovir Viread® PMPA TFV TNF
Type Single Compound
Formula C9H14N5O4P
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human vaginal epithelial VK2 E6/E7 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

tenofovir-loaded Eudragit S-100® nanoparticles

Hydrodynamic diameter: 201.2 - 251.6 nm

Medium: sodium citrate dihydrate aqueous solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • Eudragit S-100®
  1. 4sTBRYOo
Product

tenofovir-loaded Eudragit S-100® nanoparticles

Hydrodynamic diameter: 175.6 - 214.8 nm

Medium: sodium citrate dihydrate aqueous solution

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • Eudragit S-100®
  1. y2pEk05S
Product

tenofovir-loaded Eudragit S-100® nanoparticles

Hydrodynamic diameter: 151.0 - 192.6 nm

Medium: sodium citrate dihydrate aqueous solution

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • Eudragit S-100®
  1. ViLUTfYT
Product

tenofovir-loaded Eudragit S-100® nanoparticles

Size: not specified

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • Eudragit S-100®
  1. 5Epg5k1q
Product

tenofovir-loaded Eudragit S-100® nanoparticles

Hydrodynamic diameter: 105.7 - 138.9 nm

Medium: sodium citrate dihydrate aqueous solution

Support: none

References

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