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PEGylated palmitic acid-conjugated siRNA-loaded poly(ethylene glycol)-b-poly(2-(dimethylamino) ethyl methacrylate-co-butyl methacrylate) nanopolyplexes colloid

Based on

1 Articles
2016 Most recent source

Composition

1

poly(ethylene glycol)-b-poly(2-(dimethylamino) ethyl methacrylate-co-butyl methacrylate)

PEG-b-p(DMAEMA-co-BMA)
Type Polymer
Formula
Role carriers
2

palmitic acid-conjugated small interfering RNA

palmitic acid-conjugated siRNA
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Source
colloidal stability dependent on sodium chloride concentration

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Applications

Area Application Source
genetic engineering

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
human epithelial breast cancer MDA-MB-231 cells constitutively expressing luciferase

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • palmitic acid-conjugated small interfering RNA
  • poly(ethylene glycol)-b-poly(2-(dimethylamino) ethyl methacrylate-co-butyl methacrylate)
  1. 6S8T8YMX9aE2ApTym1nVG
  2. VMG5zC
Product

PEGylated palmitic acid-conjugated siRNA-loaded poly(ethylene glycol)-b-poly(2-(dimethylamino) ethyl methacrylate-co-butyl methacrylate) nanopolyplexes colloid

References

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