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doxorubicin and mitomycin C-loaded polymer-lipid hybrid nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

hydrolyzed polymer of epoxidized soybean oil

HPESO
Type Complex Compound
Formula
Role core
2

1-tridecanecarboxylic acid

tetradecanoic acid myristic acid mystric acid MAc MA
Type Single Compound
Formula C14H28O2
Role loaded material
3

polyethylene glycol 40 stearate

polyethylene glycol 40SA PEG 40SA
Type Polymer
Formula
Role loaded material
4

polyethylene glycol 100 stearate

polyethylene glycol 100SA PEG 100SA
Type Polymer
Formula
Role loaded material
5

doxorubicin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material
6

mitomycin C

mitomycin C mitomycin mytomycin MMC
Type Single Compound
Formula C15H18N4O5
Role loaded material
7

Pluronic F-68

PF-68
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on drugs

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
Balb/c mouse with murine breast cancer EMT6/WT cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • polyethylene glycol 100 stearate
  • mitomycin C
  • 1-tridecanecarboxylic acid
See all (4)
  1. JleGlwF
Product

doxorubicin and mitomycin C-loaded polymer-lipid hybrid nanoparticles

Hydrodynamic diameter: 126 - 166 nm

Medium/Support: none

References

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