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Dox-loaded sgc8 aptamer-conjugated PEG-COOH-modified gold-coated Fe3O4 nanoroses

Based on

1 Articles
2014 Most recent source

Composition

1

gold-coated Fe3O4 nanoroses

Fe3O4@Au nanoroses
Type Nano Material
Formula
Role core
2

SH-PEG-COOH

Type Polymer
Formula
Role layer
3

capture probe

DNA
Type Biomolecule
Formula
Role layer
4

sgc8-(PEG)2-(ACG)7

Type Biomolecule
Formula
Role layer
5

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human acute lymphoblastic leukemia CCRF-CEM T-cells CCL-119

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Preparation

Method 1

Type: Chemical synthesis
Source:
  1. CItOjD2sSMz4ecYDMrqI7wKhU22shOc
Product

Dox-loaded sgc8 aptamer-conjugated PEG-COOH-modified gold-coated Fe3O4 nanoroses

Hydrodynamic diameter: ~ 115 nm

Medium/Support: none

References

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