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siRNA-loaded core-shell nanoscale coordination polymer nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

Zn(II)-bisphosphonate

(Zn-PtBp)n
Type Complex Compound
Formula
Role core
2

gemcitabine monophosphate sodium salt

Type Single Compound
Formula C9H11F2N3NaO7P
Role fillers
3

lipids

Type Complex Compound
Formula
Role layer
4

cholesterol

Type Single Compound
Formula C27H46O
Role fillers
5

pooled DSPE-siRNA conjugates

Type Complex Compound
Formula
Role fillers

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
Balb/c mouse bearing CT26 tumor

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Preparation

References

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