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RGD-modified dendrimer-encapsulated platinum nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

PAMAM dendrimer G5

Type Polymer
Formula
Role core
2

carbonyl moiety

acetyl fragment acetyl group acetyl
Type Single Compound
Formula C2H3O-
Role layer
3

4-(N-maleimidomethyl)-cyclohexanecarboxylic acid N-hydroxysuccinimide ester

4-(N-maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester (succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate) succinimidyl-4-(N-maleimidomethyl)- cyclohexane-1-carboxylate succinimidyl 4-(N-maleimidomethyl) cyclohexane-1-carboxylate succinimidyl-4-(N-maleimidomethyl)cyclohexane-1- carboxylate succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate N-succinimidyl 4-(maleimidomethyl)cyclohexane carboxylate SMCC
Type Single Compound
Formula C16H18N2O6
Role graft
4

arginine-glycine-aspartic acid-D-phenylalanine-cysteine cyclic peptide

cyclo(L-arginylglycyl-L-alpha-aspartyl-D-phenylalanyl-L-cysteinyl) Arg-Gly-Asp-D-Phe-Cys cyclic pentapeptide cyclic Arg-Gly-Asp polypeptide cyclo(Arg-Gly-Asp-D-Phe-Cys) cyclic RGD polypeptide RGD peptide cyclic RGD cRGDfC cRGD RGD
Type Single Compound
Formula C24H34N8O7S
Role graft
5

platinum nanoparticles

Pt nanoparticles platinum NP Pt NP PtNP
Type Nano Material
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Source
irradiation-induced heating

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
UV

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Biological effects

Biological system Test details Source
male BALB/c nude mouse bearing subcutaneous MDA-MB-231-Luc tumors

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  1. oNnwgnY2iF2FpaRG
Product

RGD-modified dendrimer-encapsulated platinum nanoparticles

References

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