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doxorubicin-entrapped DNA duplex-locked mesoporous silica nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

aminosiloxane-functionalized mesoporous silica nanoparticles

aminosiloxane-functionalized MP-SiO2 NP
Type Nano Material
Formula
Role core
2

6-maleimidohexanoic acid moiety

EMCS moiety
Type Single Compound
Formula -C10H12NO3
Role layer
3

thiolated oligonucleotide duplex

thiolated nucleic acid duplex thiolated DNA duplex
Type Biomolecule
Formula
Role layer
4

doxorubicin hydrogen chloride

adriblastin hydrochloride doxorubicin hydrochloride adriamycin hydrochloride doxorubicin hydrochoride adriblastin HCl salt adriamycin HCl salt DOX hydrochloride DXR hydrochloride doxorubicin HCl DOX*HCl DOX-HCl DOX·HCl DXR HCl DXR*HCl Dox HCl Dox*HCl DOXS
Type Single Compound
Formula C27H29NO11*HCl
Role loaded material

Properties

General physical and chemical properties

Property Value Source
fluorescence dependent on potassium ion concentration

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
fluorescence spectroscopy dependent on potassium ion concentration

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Biological effects

Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  1. yktazEkFicUE
Product

doxorubicin-entrapped DNA duplex-locked mesoporous silica nanoparticles

References

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