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triclosan-loaded mixed-shell poly(ethylene glycol)-block-poly(ε-caprolactone)/poly(ε-caprolactone)-block-poly(hexane-1,6-diyl diacrylate-co-4,4'-trimethylenedipiperidine) 2-(tert-butoxycarbonylamino)ethyl ester micelles

Based on

1 Articles
2016 Most recent source

Composition

1

poly(ethylene glycol)-block-poly(ε-caprolactone)/poly(ε-caprolactone)-block-poly(hexane-1,6-diyl diacrylate-co-4,4'-trimethylenedipiperidine) 2-(tert-butoxycarbonylamino)ethyl ester mixture

PEG5k-b-PCL10k/PCL10k-b-PAE11k mixture PEG-b-PCL/PCL-b-PAE mixture
Type Complex Compound
Formula
Role carriers
2

5-chloro-2-(2,4-dichlorophenoxy)phenol

triclosan
Type Single Compound
Formula C12H7Cl3O2
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
planktonic Staphylococcus aureus ATCC12600<sup>GFP</sup>

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(ε-caprolactone)-block-poly(hexane-1,6-diyl diacrylate-co-4,4'-trimethylenedipiperidine) 2-(tert-butoxycarbonylamino)ethyl ester
  • poly(ethylene glycol)-block-poly(ε-caprolactone)
  • 5-chloro-2-(2,4-dichlorophenoxy)phenol
  1. V1mlvDIcKmIfPJR
Product

triclosan-loaded mixed-shell poly(ethylene glycol)-block-poly(ε-caprolactone)/poly(ε-caprolactone)-block-poly(hexane-1,6-diyl diacrylate-co-4,4'-trimethylenedipiperidine) 2-(tert-butoxycarbonylamino)ethyl ester micelles

Hydrodynamic diameter: ~ 153 nm

Medium: phosphate buffered saline

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • poly(ε-caprolactone)-block-poly(hexane-1,6-diyl diacrylate-co-4,4'-trimethylenedipiperidine) 2-(tert-butoxycarbonylamino)ethyl ester
  • poly(ethylene glycol)-block-poly(ε-caprolactone)
  • 5-chloro-2-(2,4-dichlorophenoxy)phenol
  1. 8ezHWeJlIySjggH
Product

triclosan-loaded mixed-shell poly(ethylene glycol)-block-poly(ε-caprolactone)/poly(ε-caprolactone)-block-poly(hexane-1,6-diyl diacrylate-co-4,4'-trimethylenedipiperidine) 2-(tert-butoxycarbonylamino)ethyl ester micelles

Hydrodynamic diameter: ~ 161 - ~ 168 nm

Medium: phosphate buffered saline

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • poly(ε-caprolactone)-block-poly(hexane-1,6-diyl diacrylate-co-4,4'-trimethylenedipiperidine) 2-(tert-butoxycarbonylamino)ethyl ester
  • poly(ethylene glycol)-block-poly(ε-caprolactone)
  • 5-chloro-2-(2,4-dichlorophenoxy)phenol
  1. 1cCnBNlIyv1u81K
Product

triclosan-loaded mixed-shell poly(ethylene glycol)-block-poly(ε-caprolactone)/poly(ε-caprolactone)-block-poly(hexane-1,6-diyl diacrylate-co-4,4'-trimethylenedipiperidine) 2-(tert-butoxycarbonylamino)ethyl ester micelles

Hydrodynamic diameter: ~ 151 nm

Medium: phosphate buffered saline

Support: none

References

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