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cisplatin-loaded PEG-PDS-wrapped mesoporous silica nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

mesoporous silica nanoparticles

MCM-41 type MSN MSN
Type Nano Material
Formula
Role core
2

poly(methacrylic acid)-graft-polyethylene glycol-graft-poly(pyridine disulfide hydrochloride)

PMA-g-PEG-g-PDS
Type Polymer
Formula
Role layer
3

cis-diammineplatinum(II) dichloride

cis-platinum(ll)diamine dichloride cis-diamminedichloroplatinum(II) cis-dichlorodiammineplatinum(II) diammineplatinum(ll) dichloride cis-diamminedichloroplatinum cis-dichlorodiamminoplatinum cis-platinum (II) Pt(NH3)2Cl2 briplatin cisplatin platinol® CDDP CISP CPt
Type Single Compound
Formula PtCl2N2H6
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
human nasopharyngeal carcinoma KB cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  1. MNS1q
Product

cisplatin-loaded PEG-PDS-wrapped mesoporous silica nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  1. Vu2v6
Product

cisplatin-loaded PEG-PDS-wrapped mesoporous silica nanoparticles

Size: not specified

Medium/Support: none

References

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