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P-DOX-loaded PDPA nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

poly (poly(propylene oxide)/poly(propylene oxide)/poly(ethylene glycol)/poly(ethylene glycol)/-C19H27N4O4/-C19H27N4O4/C50H59N5O18/C50H59N5O18)

Type Polymer
Formula
Role raw materials
2

methoxypoly(ethylene glycol)-block-[poly(2-(diisopropylamino)ethyl methacrylate)-random-2-hydroxyethyl methacrylate cypate ester)]

Type Polymer
Formula
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
irradiation-induced heating dependent on concentration

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
adriamycin-resistant human breast cancer (MCF-7) cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • methoxypoly(ethylene glycol)-block-[poly(2-(diisopropylamino)ethyl methacrylate)-random-2-hydroxyethyl methacrylate cypate ester)]
  • poly (poly(propylene oxide)/poly(propylene oxide)/poly(ethylene glycol)/poly(ethylene glycol)/-C19H27N4O4/-C19H27N4O4/C50H59N5O18/C50H59N5O18)
  1. mRcTaVTvjRNIOBvmNyVyJ749bV
Product

P-DOX-loaded PDPA nanoparticles

Hydrodynamic diameter: 31.6 - 32.4 nm

Size: ~ 30 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • methoxypoly(ethylene glycol)-block-[poly(2-(diisopropylamino)ethyl methacrylate)-random-2-hydroxyethyl methacrylate cypate ester)]
  • poly (poly(propylene oxide)/poly(propylene oxide)/poly(ethylene glycol)/poly(ethylene glycol)/-C19H27N4O4/-C19H27N4O4/C50H59N5O18/C50H59N5O18)
  1. C9qGyPGFf463sWf6zEHR5upQG1
Product

P-DOX-loaded PDPA nanoparticles

Hydrodynamic diameter: 49.4 - 58.6 nm

Medium/Support: none

References

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