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doxorubicin-loaded FITC-labeled siRNA-loaded poly(amido amine) dendrimer-terminated disulfide-linked branched polyethylene glycol hollow nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

Vacuous

Type
Formula
Role core
2

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material
3

poly(amido amine) dendrimer-terminated disulfide-linked branched polyethylene glycol

PAMAM G2/bPEG hybrid polymer PAMAM G2-terminated bPEG
Type Polymer
Formula
Role layer
4

FITC-labeled siRNA

Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
confocal laser scanning microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
human embryonic kidney 293 cell line (HEK293)

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • adriblastin
  1. C3bMFGlIzVJZsic
  2. 4LMxTpUFr7oXo
Product

doxorubicin-loaded FITC-labeled siRNA-loaded poly(amido amine) dendrimer-terminated disulfide-linked branched polyethylene glycol hollow nanoparticles

Hydrodynamic diameter: ~ 170 - 230 nm

Medium: sodium chloride/water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • adriblastin
  1. 7OudmeJ3S6AAbMe
  2. 8s9YYu6wRGlgp
Product

doxorubicin-loaded FITC-labeled siRNA-loaded poly(amido amine) dendrimer-terminated disulfide-linked branched polyethylene glycol hollow nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • adriblastin
  1. Q2Nikrw6L9V6crY
  2. D9PLDvSdK4OGl
Product

doxorubicin-loaded FITC-labeled siRNA-loaded poly(amido amine) dendrimer-terminated disulfide-linked branched polyethylene glycol hollow nanoparticles

Hydrodynamic diameter: ~ 140 - 200 nm

Medium: sodium chloride/water

Support: none

Method 4

Type: Physical formation
Source:
Product

doxorubicin-loaded FITC-labeled siRNA-loaded poly(amido amine) dendrimer-terminated disulfide-linked branched polyethylene glycol hollow nanoparticles

Size: not specified

Medium/Support: none

References

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